The origin of eukaryotes

John Maynard Smith

As I have said several times in this blog, the theory of evolution is now well established. However, it is far from explaining everything. Many mysteries still remain. I listed some of them in a previous post. A book by J. Maynard Smith and E. Szathmáry, The Major Transitions in Evolution (Oxford University Press, 1995), describes them in more detail.

One of these problems refers to the changes of level that have taken place in the history of life, which I made the central idea of ​​my book The Fifth Level of Evolution. As its title implies, during evolution, things have not happened in an orderly or stable manner. At various points, there were changes of state (similar to those in physics) where evolution passed a critical point that made it possible to reach higher levels and opened up huge new fields in the configuration space. These points are the following:

Giant Viruses

John Maynard Smith

In 1966, H.J. Muller defined living beings as follows: Any being capable of multiplying with inheritance and variation. With this definition, which prioritizes reproduction and evolution as the definition of life, viruses should be considered as living beings. Other biologists, such as John Maynard Smith, thought that this criterion was too broad. It would mean that nucleic acids are alive, since they are capable of reproducing with inheritance and variation. That is why they propose adding another criterion: A living being is capable of reproducing and metabolizing. This would exclude nucleic acids, and therefore viruses, which are nucleic acids enclosed in a protein capsule, and viroids, which are isolated nucleic acids.

The tree of life, the family tree of all species of living beings, seems to indicate that all beings formed by one or more cells descend from a single individual, the first living being, which is called LUCA (Last Universal Common Ancestor). As I said in another post, some think that perhaps LUCA was not a single individual, but a network of individuals. But where do viruses come from?